Associate Professor of Biomedical Engineering
Instrumented Microphysiological Analytic Platforms for Precision Measurement and Manipulation of Tissue Functions
My laboratory research focuses on the development of human organ/tissue-on-a-chip platform technologies for disease modeling, drug screening, and precision medicine. In this talk, I will introduce instrumented microphysiological systems integrated with biosensors and/or actuators developed in our laboratory, including high-throughput 3D engineered heart tissues for space biology, micro/nano-fabricated platforms for drug-induced cardiotoxicity, and a microfluidic blood-brain barrier model for drug delivery studies. Using our multi-scale biofabrication techniques, I will highlight how our biomimetic tissue chip models help to gain a better understanding of the structure-function relationship in complex 3D tissues and serve as emerging platforms for disease biology studies and biotherapeutic development.